Infusion & Injection Coding Compliance: Protect Your Reimbursement

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One infusion or injection coding error can cost you reimbursement—master compliance rules to prevent denials, audits, and revenue loss.

1. Infusion & Injection Coding Compliance: 2026 CPT®, CMS, NCCI, Modifier & Drug Reporting Updates

Pre-recorded Webinar

Infusion and injection coding mistakes can quickly lead to denied claims, underpayments, compliance exposure, and audit risk. One wrong initial code, incorrect infusion hierarchy, missing time documentation, improper modifier use, or unsupported drug reporting can create serious reimbursement and compliance issues.

With the latest CPT® guidance, CMS rules, NCCI edits, HCPCS drug reporting requirements, and modifier updates continuing to impact infusion and injection billing, healthcare organizations cannot afford outdated coding practices.

This practical webinar will provide a comprehensive review of infusion and injection coding, documentation, billing, and compliance requirements. Attendees will learn how to accurately report hydration, therapeutic, prophylactic, diagnostic, and chemotherapy administration services while reducing common coding errors that trigger denials and audits.

The session will explain how to correctly apply CPT® hierarchy rules, select the appropriate initial, sequential, and concurrent infusion codes, and support time-based reporting with proper documentation. Both physician and facility billing considerations will be addressed to help participants understand how coding rules apply in different care settings.

Attendees will also gain clarity on CMS and NCCI updates, HCPCS J-codes, NDC reporting, drug reimbursement methodologies, and key modifier requirements including 59, JW, and JZ. Real-world examples and case scenarios will help participants connect the rules to practical billing and coding situations.

Whether you are responsible for coding, billing, documentation, auditing, revenue cycle, or claim submission, this webinar will help you strengthen compliance, prevent avoidable denials, and improve accuracy in infusion and injection reporting.

2. Denials, Appeals and Prior Authorization: How to Protect Reimbursement

Pre-recorded Webinar

Claim denials are an important part of the revenue cycle and a reason for low reimbursements.  Too often processing denials is put on the back burner to charge processing and payment posting.  This webinar is going to look at the most common denials and give attendees valuable information on how to better manage denials so that reimbursement is not left on the table.  We will discuss methods of creating a process to ensure that timely filing limits are met and learn how tracking denials can assist in understanding changes in insurance carrier policies.

Webinar Highlights

1. Infusion & Injection Coding Compliance: 2026 CPT®, CMS, NCCI, Modifier & Drug Reporting Updates

Session Highlights:

This session will cover:

  • CPT® codes 96360–96549 and how they apply to infusion and injection services.
  • Current coding rules for hydration, therapeutic, diagnostic, prophylactic, and chemotherapy administration.
  • How to determine the correct initial service using CPT® hierarchy rules.
  • Sequential and concurrent infusion reporting explained with examples.
  • Time-based coding requirements and documentation expectations.
  • Common billing mistakes that lead to denials, recoupments, and audit findings.
  • NCCI edits and CMS guidance impacting infusion coding compliance.
  • HCPCS J-code and NDC reporting considerations.
  • Drug reimbursement methodologies including ASP, AWP, and AMP.
  • Correct use of modifiers 59, JW, and JZ.
  • Facility vs. professional billing rules and key differences.
  • Practical coding examples and real-world scenarios.
2. Denials, Appeals and Prior Authorization: How to Protect Reimbursement

Session Highlights:

  • Finding and understanding denial and remark codes
  • Common denials and how they will need to be reconciled
  • NCCI policies that create denials
  • Creating a denials management process based staff and technology
  • Trending denials using your practice management system
  • The appeals process
  • Writing an effective appeal
  • Knowing what to do when an appeal is not enough

Webinar Should Attend:

Infusion and injection coding is a high-risk area because it involves multiple layers of rules: CPT® hierarchy, time-based reporting, drug coding, modifier usage, documentation support, NCCI edits, and payer-specific claim scrutiny and Reimbursement team, collectors, biller, coder, revenue cycle manager, administrator, cash poster, claims adjuster, claims manager.

1. Infusion & Injection Coding Compliance: 2026 CPT®, CMS, NCCI, Modifier & Drug Reporting Updates

Session Highlights:

This session will cover:

  • CPT® codes 96360–96549 and how they apply to infusion and injection services.
  • Current coding rules for hydration, therapeutic, diagnostic, prophylactic, and chemotherapy administration.
  • How to determine the correct initial service using CPT® hierarchy rules.
  • Sequential and concurrent infusion reporting explained with examples.
  • Time-based coding requirements and documentation expectations.
  • Common billing mistakes that lead to denials, recoupments, and audit findings.
  • NCCI edits and CMS guidance impacting infusion coding compliance.
  • HCPCS J-code and NDC reporting considerations.
  • Drug reimbursement methodologies including ASP, AWP, and AMP.
  • Correct use of modifiers 59, JW, and JZ.
  • Facility vs. professional billing rules and key differences.
  • Practical coding examples and real-world scenarios.
2. Denials, Appeals and Prior Authorization: How to Protect Reimbursement

Session Highlights:

    • Finding and understanding denial and remark codes
    • Common denials and how they will need to be reconciled
    • NCCI policies that create denials
    • Creating a denials management process based staff and technology
    • Trending denials using your practice management system
    • The appeals process
    • Writing an effective appeal
    • Knowing what to do when an appeal is not enough
1. Infusion & Injection Coding Compliance: 2026 CPT®, CMS, NCCI, Modifier & Drug Reporting Updates

Session Agenda:

  • Overview of infusion and injection coding in 2026.
  • CPT® terminology and infusion hierarchy rules.
  • Review of CPT® codes 96360–96549.
  • Hydration vs. therapeutic, diagnostic, and prophylactic infusions.
  • Chemotherapy administration coding requirements.
  • Initial, sequential, and concurrent infusion reporting.
  • Time-based coding and documentation requirements.
  • Modifier usage: 59, JW, and JZ.
  • NCCI edits and CMS compliance considerations.
  • HCPCS J-codes, NDC reporting, and drug reimbursement.
  • Facility vs. professional billing considerations.
  • Case studies and common claim scenarios.
  • Q&A session.
2. Denials, Appeals and Prior Authorization: How to Protect Reimbursement

Session Agenda:

  • We will review the denial and remark codes
  • Locate common claims edits that also code denials
  • Walk through   recognizing trends in denials that can assist in seeing policy or coding changes
  • When the denial is incorrect it is important to write an effective appeal
  • Prior authorization
  • Medical Necessity
  • Checklists for all of the steps
1. Infusion & Injection Coding Compliance: 2026 CPT®, CMS, NCCI, Modifier & Drug Reporting Updates

Session Objectives:

After attending this webinar, participants will be able to:

  1. Understand the CPT® coding structure for infusion and injection services.
  2. Apply infusion hierarchy rules when selecting the correct initial service.
  3. Distinguish between hydration, therapeutic, diagnostic, prophylactic, and chemotherapy infusions.
  4. Accurately report initial, sequential, and concurrent infusion services.
  5. Apply time-based reporting rules correctly for infusion and injection coding.
  6. Use modifiers 59, JW, and JZ appropriately and compliantly.
  7. Apply NCCI guidelines to reduce coding errors and prevent claim denials.
  8. Identify documentation requirements needed to support compliant billing.
  9. Understand CMS updates impacting infusion, injection, and drug reporting.
2. Denials, Appeals and Prior Authorization: How to Protect Reimbursement

Session Objectives:

  • The first step of denials management is understanding the transaction codes sets
  • Confirm that a denial is valid.  Once a denial is found to be incorrect, it has to be
  • Show how to appeal when the denial is incorrect.
  • Organizing the process so it allows multiple staff
  • This process will also assist in identifying insurance company trends
  • Best practice for obtaining Prior Authorization
  • Submitting affective appeals- what should they say

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Lynn M. Anderanin

CPC, CPMA, CPC-I, CPPM, COSC

Lynn Anderanin is a nationally recognized expert in orthopedic coding and compliance with over 40 years of experience. She is a Coding Compliance Manager. Lynn frequently speaks on CPT®, ICD-10, and compliance topics, specializing in orthopedic and E/M services.

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